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Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy

The so-called immune checkpoints are pathways that regulate the timing and intensity of the immune response to avoid an excessive reaction and to protect the host from autoimmunity. Immune checkpoint inhibitors (ICIs) are designed to target the negative regulatory pathways of T cells, and they have...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lecis, Daniele, Sangaletti, Sabina, Colombo, Mario P., Chiodoni, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563035/
https://ncbi.nlm.nih.gov/pubmed/31060225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050624
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