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AID-dependent histone acetylation is detected in immunoglobulin S regions

Class switch recombination (CSR) is regulated by the expression of activation-induced deaminase (AID) and germline transcripts (GLTs). AID-dependent double-strand breaks (DSBs) are introduced into switch (S) regions and stimulate CSR. Although histone acetylation (Ac) has been well documented in tra...

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Detalhes bibliográficos
Main Authors: Wang, Lili, Whang, Naree, Wuerffel, Robert, Kenter, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118092/
https://ncbi.nlm.nih.gov/pubmed/16418396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051774
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