TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque

Acute coronary syndromes (ACS) are precipitated by a rupture of the atherosclerotic plaque, often at the site of T cell and macrophage infiltration. Here, we show that plaque-infiltrating CD4 T cells effectively kill vascular smooth muscle cells (VSMC). VSMCs sensitive to T cell–mediated killing exp...

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Bibliographic Details
Main Authors: Sato, Kayoko, Niessner, Alexander, Kopecky, Stephen L., Frye, Robert L., Goronzy, Jörg J., Weyand, Cornelia M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118078/
https://ncbi.nlm.nih.gov/pubmed/16418392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051062
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