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EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability

Atherosclerotic plaque instability is precipitated by vascular smooth muscle cell apoptosis in the fibrous cap, weakening it and leading to plaque rupture. We previously showed that reducing smooth muscle cell apoptosis with soluble N-cadherin (SNC) increased features of plaque stability. We have no...

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書目詳細資料
發表在:Mol Ther Methods Clin Dev
Main Authors: Lyon, Cressida A, Johnson, Jason L, White, Stephen, Sala-Newby, Graciela B, George, Sarah J
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362368/
https://ncbi.nlm.nih.gov/pubmed/26015951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.4
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