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EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability

Atherosclerotic plaque instability is precipitated by vascular smooth muscle cell apoptosis in the fibrous cap, weakening it and leading to plaque rupture. We previously showed that reducing smooth muscle cell apoptosis with soluble N-cadherin (SNC) increased features of plaque stability. We have no...

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Библиографические подробности
Опубликовано в: :Mol Ther Methods Clin Dev
Главные авторы: Lyon, Cressida A, Johnson, Jason L, White, Stephen, Sala-Newby, Graciela B, George, Sarah J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362368/
https://ncbi.nlm.nih.gov/pubmed/26015951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.4
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