Inhibition of N-cadherin retards smooth muscle cell migration and intimal thickening via induction of apoptosis

OBJECTIVES: Inhibition of vascular smooth muscle cell (VSMC) migration is a potential strategy for reducing intimal thickening during in-stent restenosis and vein graft failure. In this study, we examined the effect of disrupting the function of the VSMC adhesion molecule, N-cadherin, using antagoni...

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Detalhes bibliográficos
Main Authors: Lyon, Cressida A., Koutsouki, Evgenia, Aguilera, Concepcion M., Blaschuk, Orest W., George, Sarah Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Basic Research Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977853/
https://ncbi.nlm.nih.gov/pubmed/20630685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2010.05.096
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