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Statins reduce endothelial cell apoptosis via inhibition of TRAIL expression on activated CD4 T cells in acute coronary syndrome

OBJECTIVE: Statins reduce cardiovascular-related morbidity and mortality, but their effects on inflammation in atherosclerosis are not fully understood. We investigated whether statins can modulate cytotoxic functions of CD4 T cells in acute coronary syndrome (ACS). METHODS AND RESULTS: Fresh CD4 T...

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Main Authors: Sato, Kayoko, Nuki, Toshiyuki, Gomita, Keiko, Weyand, Cornelia M., Hagiwara, Nobuhisa
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914144/
https://ncbi.nlm.nih.gov/pubmed/20430391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.03.034
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