Uptake of Leishmania major by dendritic cells is mediated by Fcγ receptors and facilitates acquisition of protective immunity

Uptake of Leishmania major by dendritic cells (DCs) results in activation and interleukin (IL)-12 release. Infected DCs efficiently stimulate CD4(−) and CD8(−) T cells and vaccinate against leishmaniasis. In contrast, complement receptor 3–dependent phagocytosis of L. major by macrophages (MΦ) leads...

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Main Authors: Woelbing, Florian, Kostka, Susanna Lopez, Moelle, Katharina, Belkaid, Yasmine, Sunderkoetter, Cord, Verbeek, Sjef, Waisman, Ari, Nigg, Axel P., Knop, Juergen, Udey, Mark C., von Stebut, Esther
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118064/
https://ncbi.nlm.nih.gov/pubmed/16418399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052288
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