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Systematic identification of essential genes by in vitro mariner mutagenesis

Although the complete DNA sequences of several microbial genomes are now available, nearly 40% of the putative genes lack identifiable functions. Comprehensive screens and selections for identifying functional classes of genes are needed to convert sequence data into meaningful biological informatio...

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Bibliografiske detaljer
Main Authors: Akerley, Brian J., Rubin, Eric J., Camilli, Andrew, Lampe, David J., Robertson, Hugh M., Mekalanos, John J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21179/
https://ncbi.nlm.nih.gov/pubmed/9671781
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