Systematic identification of essential genes by in vitro mariner mutagenesis

Although the complete DNA sequences of several microbial genomes are now available, nearly 40% of the putative genes lack identifiable functions. Comprehensive screens and selections for identifying functional classes of genes are needed to convert sequence data into meaningful biological informatio...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Akerley, Brian J., Rubin, Eric J., Camilli, Andrew, Lampe, David J., Robertson, Hugh M., Mekalanos, John J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8927
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