Small intestinal CD8(+)TCRγδ(+)NKG2A(+) intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease

Intraepithelial lymphocytes (IELs) bearing the γδ TCR are more abundant in the small intestinal mucosa of patients with celiac disease (CD) compared with healthy individuals. However, their role in disease pathogenesis is not well understood. Here, we investigated the functional attributes of TCRγδ(...

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Hlavní autoři: Bhagat, Govind, Naiyer, Afzal J., Shah, Jayesh G., Harper, Jason, Jabri, Bana, Wang, Timothy C., Green, Peter H.R., Manavalan, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117760/
https://ncbi.nlm.nih.gov/pubmed/18064301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30989
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