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Small intestinal CD8(+)TCRγδ(+)NKG2A(+) intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease

Intraepithelial lymphocytes (IELs) bearing the γδ TCR are more abundant in the small intestinal mucosa of patients with celiac disease (CD) compared with healthy individuals. However, their role in disease pathogenesis is not well understood. Here, we investigated the functional attributes of TCRγδ(...

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Detalhes bibliográficos
Main Authors: Bhagat, Govind, Naiyer, Afzal J., Shah, Jayesh G., Harper, Jason, Jabri, Bana, Wang, Timothy C., Green, Peter H.R., Manavalan, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117760/
https://ncbi.nlm.nih.gov/pubmed/18064301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30989
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