Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas

Hepatocellular carcinoma (HCC) is the major primary malignant tumor in the human liver, but the molecular changes leading to liver cell transformation remain largely unknown. The Wnt-β-catenin pathway is activated in colon cancers and some melanoma cell lines, but has not yet been investigated in HC...

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Main Authors: Coste, Alix de La, Romagnolo, Béatrice, Billuart, Pierre, Renard, Claire-Angélique, Buendia, Marie-Annick, Soubrane, Olivier, Fabre, Monique, Chelly, Jamel, Beldjord, Cherif, Kahn, Axel, Perret, Christine
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1998
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC21165/
https://ncbi.nlm.nih.gov/pubmed/9671767
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