Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas

Hepatocellular carcinoma (HCC) is the major primary malignant tumor in the human liver, but the molecular changes leading to liver cell transformation remain largely unknown. The Wnt-β-catenin pathway is activated in colon cancers and some melanoma cell lines, but has not yet been investigated in HC...

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Bibliografische gegevens
Hoofdauteurs: Coste, Alix de La, Romagnolo, Béatrice, Billuart, Pierre, Renard, Claire-Angélique, Buendia, Marie-Annick, Soubrane, Olivier, Fabre, Monique, Chelly, Jamel, Beldjord, Cherif, Kahn, Axel, Perret, Christine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 1998
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21165/
https://ncbi.nlm.nih.gov/pubmed/9671767
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