Nuclear Accumulation of Mutated β-Catenin in Hepatocellular Carcinoma Is Associated with Increased Cell Proliferation

Inappropriate activation of the Wnt pathway resulting from β-catenin gene alterations has recently been implicated in the development of hepatocellular carcinoma (HCC). To explore the in vivo effects of mutated β-catenin, HCC specimens from 32 patients carrying one or several tumors were screened fo...

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Main Authors: Nhieu, Jeanne Tran Van, Renard, Claire Angélique, Wei, Yu, Cherqui, Daniel, Zafrani, Elie Serge, Buendia, Marie Annick
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 1999
Teme:
Short Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866892/
https://ncbi.nlm.nih.gov/pubmed/10487827
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