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Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens

HLA class II antigens are heterodimeric cell surface glycoproteins that interact with antigenic peptides to form complexes recognizable by CD4- positive T cells. During their biosynthesis, class II antigens are retained in a post-Golgi compartment in association with the invariant chain, which disso...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2116304/
https://ncbi.nlm.nih.gov/pubmed/2391366
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