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Invariant Chain Modulates HLA Class II Protein Recycling and Peptide Presentation in Nonprofessional Antigen Presenting Cells

The expression of MHC class II molecules and the invariant chain (Ii) chaperone, is coordinately regulated in professional antigen presenting cells (APC). Ii facilitates class II subunit folding as well as transit and retention in mature endosomal compartments rich in antigenic peptides in these APC...

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Detalhes bibliográficos
Main Authors: Haque, Azizul, Hajiaghamohseni, Laela M., Li, Ping, Toomy, Katherine, Blum, Janice S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254578/
https://ncbi.nlm.nih.gov/pubmed/18067883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2007.10.005
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