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The ornithine transcarbamylase leader peptide directs mitochondrial import through both its midportion structure and net positive charge
The cytoplasmically synthesized precursor of the mitochondrial matrix enzyme, ornithine transcarbamylase (OTC), is targeted to mitochondria by its NH2-terminal leader peptide. We previously established through mutational analysis that the midportion of the OTC leader peptide is functionally required...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
1987
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2114782/ https://ncbi.nlm.nih.gov/pubmed/3624306 |
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