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The ornithine transcarbamylase leader peptide directs mitochondrial import through both its midportion structure and net positive charge

The cytoplasmically synthesized precursor of the mitochondrial matrix enzyme, ornithine transcarbamylase (OTC), is targeted to mitochondria by its NH2-terminal leader peptide. We previously established through mutational analysis that the midportion of the OTC leader peptide is functionally required...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114782/
https://ncbi.nlm.nih.gov/pubmed/3624306
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