Arginine in the leader peptide is required for both import and proteolytic cleavage of a mitochondrial precursor.

Most mitochondrial proteins are encoded in the nucleus and translated in the cytoplasm as larger precursors containing NH2-terminal "leader" peptides, which are strikingly basic in overall amino acid composition. Recent experiments indicate that these leader peptides are both necessary and sufficien...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Horwich, A L, Kalousek, F, Rosenberg, L E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390471/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3895227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.15.4930
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