Arginine in the leader peptide is required for both import and proteolytic cleavage of a mitochondrial precursor.
Most mitochondrial proteins are encoded in the nucleus and translated in the cytoplasm as larger precursors containing NH2-terminal "leader" peptides, which are strikingly basic in overall amino acid composition. Recent experiments indicate that these leader peptides are both necessary and sufficien...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390471/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3895227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.15.4930 |
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