Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans

The tumor suppressor gene FHIT encompasses the common human chromosomal fragile site at 3p14.2 and numerous cancer cell biallelic deletions. To study Fhit function we cloned and characterized FHIT genes from Drosophila melanogaster and Caenorhabditis elegans. Both genes code for fusion proteins in w...

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Bibliografiske detaljer
Main Authors: Pekarsky, Yuri, Campiglio, Manuela, Siprashvili, Zurab, Druck, Teresa, Sedkov, Yurii, Tillib, Sergei, Draganescu, Alexandra, Wermuth, Peter, Rothman, Joel H., Huebner, Kay, Buchberg, Arthur M., Mazo, Alexander, Brenner, Charles, Croce, Carlo M.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21147/
https://ncbi.nlm.nih.gov/pubmed/9671749
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