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Chymotrypsin substrate analogues inhibit endocytosis of insulin and insulin receptors in adipocytes

To explore the possible role of proteolytic step(s) in receptor- mediated endocytosis of insulin, the effects of inhibitors of various classes of proteases on the internalization process were studied in isolated rat adipocytes. Intracellular accumulation of receptor-bound 125I-insulin at 37 degrees...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114384/
https://ncbi.nlm.nih.gov/pubmed/2877995
Etiketak: Etiketa erantsi
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