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Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases

Nerve growth factor (NGF) mediates the phosphorylation of tyrosine hydroxylase in PC12 cells on two distinct peptide fragments, separable by two-dimensional tryptic phosphopeptide mapping (phosphopeptides T1 and T3). Phorbol diester derivatives capable of activating Ca+2/phospholipid-dependent prote...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114293/
https://ncbi.nlm.nih.gov/pubmed/2875079
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