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Intersubunit signaling in RecBCD enzyme, a complex protein machine regulated by Chi hot spots

The Escherichia coli RecBCD helicase–nuclease, a paradigm of complex protein machines, initiates homologous genetic recombination and the repair of broken DNA. Starting at a duplex end, RecBCD unwinds DNA with its fast RecD helicase and slower RecB helicase on complementary strands. Upon encounterin...

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Bibliographic Details
Main Authors: Amundsen, Susan K., Taylor, Andrew F., Reddy, Manjula, Smith, Gerald R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113030/
https://ncbi.nlm.nih.gov/pubmed/18079176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1605807
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