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THE KEY REGULATORS OF ADULT T HELPER CELL RESPONSES, STAT6 AND T-BET, ARE ESTABLISHED IN EARLY LIFE IN MICE
Murine neonatal immunity is typically Th2-biased. This is characterized by high-level IL-4 production at all phases of the immune response and poor IFN-γ memory responses. The differential expression of Th1/Th2 cytokines by neonates and adults could arise if the critical regulators of Th differentia...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2112774/ https://ncbi.nlm.nih.gov/pubmed/16568497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200535563 |
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