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Isolation of Chinese hamster ovary cell mutants requiring the continuous presence of taxol for cell division

Chinese hamster ovary (CHO) cell mutants resistant to the cytotoxic effects of taxol and requiring the drug for normal growth were isolated in a single step. One of these mutant cell lines, Tax-18, fails to divide in the absence of taxol; instead, the cells become larger, rounder, flatter, and multi...

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Dettagli Bibliografici
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1983
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2112477/
https://ncbi.nlm.nih.gov/pubmed/6134736
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