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Crystal structure of the C-terminal domain of Ebola virus VP30 reveals a role in transcription and nucleocapsid association

Transcription of the highly pathogenic Ebola virus depends on VP30, a nucleocapsid-associated Ebola virus-specific transcription factor. The transcription activator VP30 was shown to play an essential role in Ebola virus replication, most likely by stabilizing nascent mRNA. Here we present the cryst...

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Detalhes bibliográficos
Main Authors: Hartlieb, Bettina, Muziol, Tadeusz, Weissenhorn, Winfried, Becker, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111399/
https://ncbi.nlm.nih.gov/pubmed/17202263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606730104
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