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A C-terminal motif found in the β(2)-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na(+)/H(+) exchanger regulatory factor family of PDZ proteins
The Na(+)/H(+) exchanger regulatory factor (NHERF) binds to the tail of the β(2)-adrenergic receptor and plays a role in adrenergic regulation of Na(+)/H(+) exchange. NHERF contains two PDZ domains, the first of which is required for its interaction with the β(2) receptor. Mutagenesis studies of the...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The National Academy of Sciences
1998
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21104/ https://ncbi.nlm.nih.gov/pubmed/9671706 |
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