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Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-d-aspartic acid-receptors and phospholipase A(2)

Repetitive spreading depression (SD) waves, involving depolarization of neurons and astrocytes and up-regulation of glucose consumption, is thought to lower the threshold of neuronal death during and immediately after ischemia. Using rat models for SD and focal ischemia we investigated the expressio...

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Detalhes bibliográficos
Main Authors: Miettinen, Susanna, Fusco, Francesca R., Yrjänheikki, Juha, Keinänen, Riitta, Hirvonen, Timo, Roivainen, Reina, Närhi, Matti, Hökfelt, Tomas, Koistinaho, Jari
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21079/
https://ncbi.nlm.nih.gov/pubmed/9177247
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