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Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

Viral and transposon vectors have been employed in gene therapy as well as functional genomics studies. However, the goals of gene therapy and functional genomics are entirely different; gene therapists hope to avoid altering endogenous gene expression (especially the activation of oncogenes), where...

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Detalhes bibliográficos
Main Authors: Hackett, Christopher S, Geurts, Aron M, Hackett, Perry B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106846/
https://ncbi.nlm.nih.gov/pubmed/18047689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s12
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