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Germline mutagenesis mediated by Sleeping Beauty transposon system in mice

Following the descovery of its transposition activity in mammalian culture systems, the Sleeping Beauty (SB) transposon has since been applied to achieve germline mutagenesis in mice. Initially, the transposition efficiency was found to be low in cultured systems, but its activity in germ cells was...

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書目詳細資料
Main Authors: Takeda, Junji, Keng, Vincent W, Horie, Kyoji
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106844/
https://ncbi.nlm.nih.gov/pubmed/18047691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s14
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