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Germline mutagenesis mediated by Sleeping Beauty transposon system in mice

Following the descovery of its transposition activity in mammalian culture systems, the Sleeping Beauty (SB) transposon has since been applied to achieve germline mutagenesis in mice. Initially, the transposition efficiency was found to be low in cultured systems, but its activity in germ cells was...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takeda, Junji, Keng, Vincent W, Horie, Kyoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106844/
https://ncbi.nlm.nih.gov/pubmed/18047691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s14
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