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In vivo IL‐10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF‐β in the lung
BACKGROUD: Idiopathic pulmonary fibrosis is a devastating disorder for which there is no effective treatment. Transforming growth factor (TGF)‐β plays a critical role in provoking fibrosis. Interleukin (IL)‐10 is a potent immunosuppressive cytokine but its effect on the fibrosing process is unclear....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2104751/ https://ncbi.nlm.nih.gov/pubmed/16809410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.056317 |
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