Losartan attenuates bleomycin induced lung fibrosis by increasing prostaglandin E(2) synthesis

BACKGROUND: The angiotensin system has a role in the pathogenesis of pulmonary fibrosis. This study examines the antifibrotic effect of losartan, an angiotensin II type 1 receptor antagonist, in bleomycin induced lung fibrosis and its possible implication in the regulation of prostaglandin E(2) (PGE...

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Detalhes bibliográficos
Main Authors: Molina‐Molina, M, Serrano‐Mollar, A, Bulbena, O, Fernandez‐Zabalegui, L, Closa, D, Marin‐Arguedas, A, Torrego, A, Mullol, J, Picado, C, Xaubet, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104675/
https://ncbi.nlm.nih.gov/pubmed/16601095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.051946
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