Peptides isolated from HLA-Cw*0304 confer different degrees of protection from natural killer cell-mediated lysis

HLA class I molecules bind peptides derived from proteins degraded in the cytoplasm and display them for surveillance by the immune system. The recognition of HLA class I molecules by natural killer (NK) cells generally inhibits the lytic process. To investigate the role of peptides in the interacti...

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Bibliographic Details
Main Authors: Zappacosta, Francesca, Borrego, Francisco, Brooks, Andrew G., Parker, Kenneth C., Coligan, John E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21046/
https://ncbi.nlm.nih.gov/pubmed/9177214
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