Non-fucosylated therapeutic antibodies: the next generation of therapeutic antibodies

Therapeutic antibody IgG1 has two N-linked oligosaccharide chains bound to the Fc region. The oligosaccharides are of the complex biantennary type, composed of a trimannosyl core structure with the presence or absence of core fucose, bisecting N-acetylglucosamine (GlcNAc), galactose, and terminal si...

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Detalhes bibliográficos
Main Authors: Mori, Katsuhiro, Iida, Shigeru, Yamane-Ohnuki, Naoko, Kanda, Yutaka, Kuni-Kamochi, Reiko, Nakano, Ryosuke, Imai-Nishiya, Harue, Okazaki, Akira, Shinkawa, Toyohide, Natsume, Akihito, Niwa, Rinpei, Shitara, Kenya, Satoh, Mitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2007
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104554/
https://ncbi.nlm.nih.gov/pubmed/19003000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-007-9103-2
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