Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome

Thioredoxin reductases (Txnrd) maintain intracellular redox homeostasis in most organisms. Metazoans Txnrds also participate in signal transduction. Mouse embryos homozygous for a targeted null mutation of the txnrd1 gene, encoding the cytosolic thioredoxin reductase, were viable at embryonic day 8....

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Détails bibliographiques
Auteurs principaux: Bondareva, Alla A., Capecchi, Mario R., Iverson, Sonya V., Li, Yan, Lopez, Nathan I., Lucas, Olivier, Merrill, Gary F., Prigge, Justin R., Siders, Ashley M., Wakamiya, Maki, Wallin, Stephanie L., Schmidt, Edward E.
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099259/
https://ncbi.nlm.nih.gov/pubmed/17697936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.05.026
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