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In vitro screening for molecules that affect virus capsid assembly (and other protein association reactions)
Protein self-assembly is critical for numerous biological processes. Yet, assembly is rarely targeted by therapeutic agents, in part because it is hard to identify molecules that interfere with protein-protein interactions. Here we describe a simple fluorescence-based screen for self-association and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2099249/ https://ncbi.nlm.nih.gov/pubmed/17406612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.60 |
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