Methylation-Acetylation Interplay Activates p53 in Response to DNA Damage

p53, an important tumor suppressor protein, exerts its function mostly as a sequence-specific transcription factor and is subjected to multiple posttranslational modifications in response to genotoxic stress. Recently, we discovered that lysine methylation of p53 at K372 by Set7/9 (also known as SET...

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Autori principali: Ivanov, Gleb S., Ivanova, Tatyana, Kurash, Julia, Ivanov, Alexey, Chuikov, Sergey, Gizatullin, Farid, Herrera-Medina, Enrique M., Rauscher, Frank, Reinberg, Danny, Barlev, Nickolai A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099237/
https://ncbi.nlm.nih.gov/pubmed/17646389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00460-07
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