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Repression of kit Expression by Plzf in Germ Cells

Male mice lacking expression of Plzf, a DNA sequence-specific transcriptional repressor, show progressive germ cell depletion due to exhaustion of the spermatogonial stem cell population. This is likely due to the deregulated expression of genes controlling the switch between spermatogonial self-ren...

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Detalhes bibliográficos
Main Authors: Filipponi, Doria, Hobbs, Robin M., Ottolenghi, Sergio, Rossi, Pellegrino, Jannini, Emmanuele A., Pandolfi, Pier Paolo, Dolci, Susanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099235/
https://ncbi.nlm.nih.gov/pubmed/17664282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00479-07
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