Llwytho...

Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells

Spatial and temporal regulation of Rap1 is required for proper myosin assembly and cell adhesion during cell migration in Dictyostelium discoideum. Here, we identify a Rap1 guanosine triphosphatase–activating protein (GAP; RapGAP1) that helps mediate cell adhesion by negatively regulating Rap1 at th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jeon, Taeck J., Lee, Dai-Jen, Lee, Susan, Weeks, Gerald, Firtel, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099181/
https://ncbi.nlm.nih.gov/pubmed/18039932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705068
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