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Rap1 controls cell adhesion and cell motility through the regulation of myosin II

We have investigated the role of Rap1 in controlling chemotaxis and cell adhesion in Dictyostelium discoideum. Rap1 is activated rapidly in response to chemoattractant stimulation, and activated Rap1 is preferentially found at the leading edge of chemotaxing cells. Cells expressing constitutively ac...

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Detalhes bibliográficos
Main Authors: Jeon, Taeck J., Lee, Dai-Jen, Merlot, Sylvain, Weeks, Gerald, Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064086/
https://ncbi.nlm.nih.gov/pubmed/17371831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607072
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