An Inactivation Gate in the Selectivity Filter of KCNQ1 Potassium Channels

Inactivation is an inherent property of most voltage-gated K(+) channels. While fast N-type inactivation has been analyzed in biophysical and structural details, the mechanisms underlying slow inactivation are yet poorly understood. Here, we characterized a slow inactivation mechanism in various KCN...

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Hlavní autoři: Gibor, Gilad, Yakubovich, Daniel, Rosenhouse-Dantsker, Avia, Peretz, Asher, Schottelndreier, Hella, Seebohm, Guiscard, Dascal, Nathan, Logothetis, Diomedes E., Paas, Yoav, Attali, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2007
Témata:
Channels, Receptors, and Electrical Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098732/
https://ncbi.nlm.nih.gov/pubmed/17704175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.107987
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