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Human α-endosulfine, a possible regulator of sulfonylurea-sensitive K(ATP) channel: Molecular cloning, expression and biological properties

Sulfonylureas are a class of drugs commonly used in the management of non-insulin-dependent diabetes mellitus. Their therapeutic action results primarily from their ability to inhibit ATP-sensitive potassium (K(ATP)) channels in the plasma membrane of pancreatic β cells and thereby stimulate insulin...

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Autors principals: Heron, Lisa, Virsolvy, Anne, Peyrollier, Karine, Gribble, Fiona M., Le Cam, Alphonse, Ashcroft, Frances M., Bataille, Dominique
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20985/
https://ncbi.nlm.nih.gov/pubmed/9653196
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