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Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus
Although anatomical and neurochemical studies suggest that endogenous opioids act as neurotransmitters1–7, their roles in normal and pathophysiological regulation of synaptic transmission are not defined. Here we examine the actions of prodynorphin-derived opioid peptides in the guinea-pig hippocamp...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1993
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096733/ https://ncbi.nlm.nih.gov/pubmed/8099201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/363451a0 |
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