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Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus

Although anatomical and neurochemical studies suggest that endogenous opioids act as neurotransmitters1–7, their roles in normal and pathophysiological regulation of synaptic transmission are not defined. Here we examine the actions of prodynorphin-derived opioid peptides in the guinea-pig hippocamp...

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Bibliografiske detaljer
Main Authors: Wagner, John J., Terman, Gregory W., Chavkin, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096733/
https://ncbi.nlm.nih.gov/pubmed/8099201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/363451a0
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