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Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus

Although anatomical and neurochemical studies suggest that endogenous opioids act as neurotransmitters1–7, their roles in normal and pathophysiological regulation of synaptic transmission are not defined. Here we examine the actions of prodynorphin-derived opioid peptides in the guinea-pig hippocamp...

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Autors principals: Wagner, John J., Terman, Gregory W., Chavkin, Charles
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096733/
https://ncbi.nlm.nih.gov/pubmed/8099201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/363451a0
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