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Autoreactive B-1 B Cells: Constraints on Natural Autoantibody B Cell Antigen Receptors

B-1 B-cells constitute a distinctive population cells that are enriched for self-reactive B cell receptors (BCRs). These BCRs are encoded by a restricted set of heavy and light chains, including heavy chains that lack nontemplated nucleotide additions at the V-D and D-j joining regions. One prototyp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rowley, Ben, Tang, Lingjuan, Shinton, Susan, Hayakawa, Kyoko, Hardy, Richard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096705/
https://ncbi.nlm.nih.gov/pubmed/17889506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2007.07.020
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