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Endocytic Trafficking of Sphingomyelin Depends on Its Acyl Chain Length

To study the principles of endocytic lipid trafficking, we introduced pyrene sphingomyelins (PyrSMs) with varying acyl chain lengths and domain partitioning properties into human fibroblasts or HeLa cells. We found that a long-chain, ordered-domain preferring PyrSM was targeted Hrs and Tsg101 depend...

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Detalhes bibliográficos
Main Authors: Koivusalo, Mirkka, Jansen, Maurice, Somerharju, Pentti, Ikonen, Elina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096594/
https://ncbi.nlm.nih.gov/pubmed/17942604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0330
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