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Endocytic Trafficking of Sphingomyelin Depends on Its Acyl Chain Length

To study the principles of endocytic lipid trafficking, we introduced pyrene sphingomyelins (PyrSMs) with varying acyl chain lengths and domain partitioning properties into human fibroblasts or HeLa cells. We found that a long-chain, ordered-domain preferring PyrSM was targeted Hrs and Tsg101 depend...

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Bibliografiske detaljer
Main Authors: Koivusalo, Mirkka, Jansen, Maurice, Somerharju, Pentti, Ikonen, Elina
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096594/
https://ncbi.nlm.nih.gov/pubmed/17942604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0330
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